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近年来,抗菌素的开发惊人,但实际在治疗选择上,尚存不少迷惑之处,并且抗菌素具有不同的药理学特性和各异的副作用,如不考虑这些,会出现有害作用,并会失掉应有的药效。根据抗菌素合成机理其副作用分为:①抗菌作用发挥后的副作用(菌群紊乱等);②抗菌作用机理或毒性引起的副作用(肝毒性、肾毒性等);③药物过敏引起的副作用(药物过敏性肝脏损害等)等。各抗菌素代表的副作用如表所示。本稿以这些抗菌素引起的代表性脏器损害为中心加以论述。
In recent years, the development of antibiotics is striking, but there are still many confusion in the actual treatment options. Antibiotics have different pharmacological properties and different side effects. If they are not taken into account, they will have harmful effects and will be lost Should have the efficacy. According to the mechanism of antibiotic synthesis, its side effects are divided into: (1) side effects after antibacterial effect (such as flora disruption); (2) side effects caused by antibacterial mechanism or toxicity (liver toxicity and nephrotoxicity); Sexual liver damage, etc.) and so on. The side effects of each antibiotic are shown in the table. The manuscript to these antibiotics caused by the representative of the damage to the center to be discussed.