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病毒性心肌炎为病毒侵犯心脏后引起心肌细胞变性坏死和心肌间质炎症改变的一种疾病,可见于各年龄组,小儿尤为易患。1952年首次由急性心肌炎死婴中的心脏内分离得病毒,1957年Fletcher报道成人柯萨奇心肌炎。晚近研究表明,急性心肌炎可演变为慢性心肌病,故及早明确诊断并予以有效治疗有其十分重要的临床意义。一、发病机理现已阐明,几乎任何病毒均能引起心肌炎但主要为肠道病毒。其中以柯萨奇B组病毒之1—5型居多,其次为柯萨奇A组病毒1、4、9、16型;埃柯病毒3、6—9、22型以及灰髓炎病毒
Viral myocarditis is a disease caused by viruses that invade the heart, causing degeneration and necrosis of cardiomyocytes and changes of myocardial interstitial inflammation. It can be seen in all age groups and especially in children. The virus was first isolated in 1952 from the heart of an infant with acute myocarditis, and in 1957 Fletcher reported adult Coxsackie myocarditis. Recent studies have shown that acute myocarditis can evolve into chronic cardiomyopathy, so early diagnosis and effective treatment has its very important clinical significance. First, the pathogenesis has been clarified that almost any virus can cause myocarditis but mainly for enterovirus. Among them, Coxsackie B virus group 1-5 was the most common, followed by Coxsackie A virus group 1, 4, 9 and 16; Echovirus 3, 6-9, and 22 virus group,