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非糜烂性反流病(NERD)是胃食管反流病(GERD)疾病谱中相对独立的亚型,综合西方国家资料,NERD占GERD的50%～70%。下食管括约肌(LES)功能障碍是NERD发病的最重要因素之一,调节LES功能是治疗NERD的新方法。由于NERD患者存在胃电起搏紊乱和胃电节律的明显改变,因此设想能否通过胃电刺激仪模拟正常胃排空的电生理过程,从而纠正NERD电紊乱,减轻或消除
Non-erosive reflux disease (NERD) is a relatively independent subtype of GERD disease spectrum. According to western countries, NERD accounts for 50% -70% of GERD. Lower esophageal sphincter (LES) dysfunction is one of the most important factors in the pathogenesis of NERD. Regulating LES function is a new way to treat NERD. Because of the presence of gastric electrical pacing disorders and gastric electrical rhythm changes in patients with NERD significant changes, so imagine whether gastric electrical stimulator can simulate normal gastric emptying electrophysiological process, so as to correct NERD electrical disorder, reduce or eliminate