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目的:探讨青春期Ⅰ型糖尿病的细胞免疫功能的变化情况。方法:入选我院Ⅰ型糖尿病患者50例,为观察组,青春期健康者50例为对照组,检测免疫球蛋白(IgG、IgM、IgA)和T细胞(CD3、CD4、CD8、CD4/CD8)。结果:观察组患者T细胞分子检测值明显低于对照组;观察组患者免疫球蛋白值显著低于对照组,结果具有统计学差异(P<0.01)。结论:Ⅰ型糖尿病的细胞免疫功能在青春期有所下降,应该增强免疫功能的调节。
Objective: To investigate the changes of cellular immune function in adolescent type 1 diabetes mellitus. Methods: Fifty patients with type I diabetes mellitus were selected as observation group and 50 healthy adolescents as control group. Immunoglobulin (IgG, IgM, IgA) and T cells (CD3, CD4, CD8, CD4 / CD8) . Results: The detection value of T cells in the observation group was significantly lower than that in the control group. The immunoglobulin values in the observation group were significantly lower than those in the control group (P <0.01). Conclusion: The cellular immune function of type Ⅰ diabetes is decreased in adolescence, and the regulation of immune function should be strengthened.