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目的：探讨短暂性脑缺血发作（ＴＩＡ）病人事件相关电位（ＥＲＰ）的变化规律及其临床意义。方法：用听觉Ｏｄｄｂａｌ刺激序列ＥＲＰ、认知能力筛选试验（ＣＣＳＥ）和简易智力状态试验（ＭＭＳＥ）检测３２例ＴＩＡ病人和３０例年龄、性别、利手和教育程度相匹配的正常人。结果：病人组ＥＲＰ的Ｎ２和Ｐ３峰潜伏期较对照组显著延长（Ｐ＜０．０１），Ｎ２和Ｐ３波幅两组均无显著性差异，Ｐ３峰潜伏期（Ｐ３ＰＬ）异常率为２５％。病人组ＭＭＳＥ较对照组低（Ｐ＜０．０５），但与Ｐ３ＰＬ未见有相关性（ｒ＝－０．２４４，Ｐ＞０．１）；ＣＣＳＥ与对照组无显著差异，但与Ｐ３ＰＬ呈显著负相关（ｒ＝－０．４７３，Ｐ＜０．０１）。结论：ＴＩＡ病人存在不同程度的认知功能障碍。对认知功能障碍的早期发现，ＥＲＰ检则有临床实用价值
Objective: To investigate the changes of event-related potential (ERP) in patients with transient ischemic attack (TIA) and its clinical significance. Methods: Thirty-two TIA patients and 30 normal subjects of the same age, gender, skill and educational attainment were detected by auditory Oddbal stimulation sequence ERP, cognitive ability screening test (CCSE) and simple intelligence state test (MMSE) Results: The peak latency of N2 and P3 in patients with ERP was significantly longer than that of the control group (P <0.01). There was no significant difference between N2 and P3 amplitude in both groups. The P3PL abnormality rate was 25%. The MMSE of the patients group was lower than that of the control group (P <0.05), but no correlation with P3PL (r = -0.244, P> 0.1). There was no significant difference between the CCSE group and the control group Significant negative correlation (r = -0.473, P <0.01). Conclusion: TIA patients have different degrees of cognitive dysfunction. On the early detection of cognitive impairment, ERP test has clinical practical value