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目的:探索介入治疗下肢动脉硬化闭塞症(ASO)的临床疗效及其影响因素。方法:选择2012年10月至2013年8月我院收治的ASO患者96例,按照治疗方法将所有患者平均分成对照组和实验组,每组48例。对照组进行常规药物治疗,实验组在常规药物治疗基础上行介入手术。考察患者临床疗效及踝肱指数(ABI),并应用二元Logistic回归研究影响ASO复发的因素。结果:术后1个月、3个月、6个月、1年,随着时间的延长,ABI值呈下降趋势,且实验组患者的ABI值在各时间点均明显高于对照组,差异具有统计学意义(P<0.05)。其中对照组患者有效率为31.25%,实验组患者有效率为87.50%,实验组有效率显著高于对照组,差异具有统计学意义(P<0.05)。糖尿病和高胆固醇症可以单独影响ASO复发。结论:介入治疗ASO患者具有良好的疗效,显著提高患者的ABI,但术后需严格控制血糖和血脂。
Objective: To explore the clinical efficacy and influencing factors of interventional treatment of lower extremity arteriosclerosis obliterans (ASO). Methods: A total of 96 patients with ASO admitted to our hospital from October 2012 to August 2013 were divided equally into control group and experimental group according to the treatment method, 48 cases in each group. The control group was treated with conventional drugs. The experimental group was given routine intervention on the basis of conventional medical therapy. The clinical efficacy and ankle-brachial index (ABI) were investigated. Logistic regression was used to study the factors influencing the recurrence of ASO. Results: At 1, 3, 6 and 1 year after operation, the ABI decreased with time, and the ABI of the experimental group was significantly higher than that of the control group at each time point Statistically significant (P <0.05). The effective rate of the control group was 31.25%, the effective rate of the experimental group was 87.50%, the effective rate of the experimental group was significantly higher than that of the control group, the difference was statistically significant (P <0.05). Diabetes and hypercholesterolemia can independently affect ASO recurrence. Conclusion: Interventional treatment of patients with ASO has a good effect, significantly improve the ABI of patients, but after surgery to strictly control blood sugar and blood lipids.