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目的将凝血常规指标与新指标联合检测,通过凝血实验室指标与临床病症的紧密结合,对肝病患者的诊断治疗、病情监测、预后以及并发DIC进行研究和分析。方法采用凝固法检测PT/PA,APTT,FIB,FV:C,FVII:C,FVIII:C。结果CH组的VII水平与正常对照组比较存在显著性差异(P<0.01);LC-2组和CSH组的DD,PT,PA,V,VII,VIII,PLT,APTT和FIB水平与正常组、AH和CH组比较均存在显著性差异(P<0.01);CSH组的PT,PA和APTT水平与其它各组比较均存在显著性差异(P<0.01)。结论DD,PT,PA,APTT,FIB,V,VII,PLT水平不仅对LC-2及CSH具有很好的诊断价值,也是严重肝病与正常组、轻度肝病组之间较理想的鉴别指标。
Objective To study the coagulation routine indexes and new indexes, and to study and analyze the diagnosis, treatment, condition monitoring, prognosis and concurrent DIC of patients with liver diseases through the close combination of coagulation laboratory indexes and clinical symptoms. Methods The coagulation method was used to detect PT / PA, APTT, FIB, FV: C, FVII: C, FVIII: C. Results The levels of DD, PT, PA, V, VII, VIII, PLT, APTT and FIB in LC group and CSH group were significantly higher than those in normal control group (P <0.01) (P <0.01). The levels of PT, PA and APTT in CSH group were significantly different from those in other groups (P <0.01). Conclusion The levels of DD, PT, PA, APTT, FIB, V, VII and PLT not only have good diagnostic value for LC-2 and CSH, but also are the ideal discriminating indexes between severe liver disease and normal liver disease and mild liver disease.