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目的:探讨血清视黄醇结合蛋白(sRBP)在肾脏疾病中的临床意义。方法:选取本院78例肾脏疾病患者作为研究对象,并随即抽取同期健康者66名作为对照组,测定sRBP、尿视黄醇结合蛋白(uRBP)、尿素氮、肌酐、血β2-微球蛋白,并进行相关的统计学分析。结果:肾病患者的sRBP的结果(88.25±29.82),对照组(49.56±15.26),肾病组明显高于对照组(P<0.01)。结论:sRBP可以作为反映肾功能异常的较敏感指标,是评价肾病患者肾功能受损程度及部位的重要参数。
Objective: To investigate the clinical significance of serum retinol binding protein (sRBP) in renal diseases. Methods: Seventy-eight patients with kidney disease were selected as our study subjects, and 66 healthy controls were enrolled in this study. Serum levels of sRBP, uRBP, urea nitrogen, creatinine, blood β2-microglobulin , And related statistical analysis. Results: The results of sRBP in nephropathy patients (88.25 ± 29.82) and control group (49.56 ± 15.26), nephropathy group were significantly higher than those in control group (P <0.01). Conclusion: sRBP can be used as a sensitive index to reflect renal dysfunction and is an important parameter to evaluate the extent and location of renal dysfunction in patients with nephropathy.