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本实验以家兔离体心脏为对象,以心脏活动时左心室内压力的变化为指标,通过离体灌流法探讨夏至草对心肌收缩功能的影响。实验结果表明,一定浓度的夏至草制剂确能增加心肌收缩力,而且心肌收缩力的增加与药物浓度在一定范围内呈正相关。
In this experiment, the isolated heart of rabbits was used as a target, and the changes of left ventricle pressure during cardiac activity were used as indicators to investigate the effect of shamrock on myocardial contractile function by ex vivo perfusion. The experimental results show that a certain concentration of sinomedicine preparation can indeed increase the myocardial contractility, and the increase of myocardial contractility is positively correlated with the drug concentration within a certain range.