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筛查新生儿先天性甲状腺功能低下症是提高人口素质,降低残疾发生率的重要措施。精确、灵敏、特异的实验方法是做好这项工作的保证。我们在对实验方法进行鉴定之后,应用于大规模筛查工作之前,首先确立了本地区新生儿先天性甲状腺功能低下症的筛查切值,为确诊可疑患儿提供了依据,现报道如下。 1 材料与方法 1.1 血样采集 在新生儿出生72～96h内,由接产医院产科护士按摩足跟,用75％酒精消毒并晾干后,用一次性采血针刺破皮肤,使血液自然流出,用美国S&S~R903滤纸吸取两个血斑,要求血斑浸透滤纸正反两面,直径在1cm以上,自然晾干后放入专用的塑料中密封4～10℃冰箱保存,10d内送至济宁市妇女儿童医院筛查实验室中检测。
Screening for neonatal congenital hypothyroidism is an important measure to improve the quality of the population and reduce the incidence of disability. Accurate, sensitive and specific experimental method is to ensure that this work. We identified the experimental method, applied to large-scale screening work, first established in the region of newborn congenital hypothyroidism screening cut value, to provide a basis for the diagnosis of suspicious children, are reported below. 1 Materials and Methods 1.1 Blood Samples During neonatal birth 72 ~ 96h, obstetric nurses massage the heel by the end of the hospital, disinfected with 75% alcohol and dried, the disposable blood collection needle punctured the skin, the blood flow out naturally, With the United States S & S ~ R903 filter paper to draw two blood spots, requiring blood spots soaked in both sides of the filter paper, the diameter of 1cm or more, dry naturally into a special plastic sealed 4 ~ 10 ℃ refrigerator, 10d sent to Jining Women and Children Hospital Screening Laboratory testing.