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目的探讨地佐辛与曲马多用于老年患者肱骨内固定手术术后镇痛的效果。方法选取2013年9月－2015年1月于医院行全身麻醉下肱骨内固定手术的老年患者70例，随机分为地佐辛组（ D组）和曲马多组（ Q组）各35例。 D组术后采用地佐辛＋舒芬太尼＋昂丹司琼镇痛；Q组术后采用曲马多＋舒芬太尼＋昂丹司琼镇痛。观察2组患者术后镇痛评分（VAS）、镇静评分（Ramsay）及不良反应发生情况。结果 D组在术后0．5h、3h的VAS评分均低于Q组，差异有统计学意义（P＜0．05），D组Ramsay评分在3 h时优于Q组，差异有统计学意义（P＜0．05），D组发生不良反应的例数也少于Q组，差异有统计学意义（P＜0．05）。结论地佐辛较曲马多的镇痛镇静效果确切，且不良反应少于曲马多组，可安全用于老年患者肱骨内固定术后镇痛。“,”Objective To investigate theclinical effect of dezocine and tramadol for proximal humerus internal fixation surgery postoperative analgesia.Methods 70 cases of elderly patients with humerus internal fixation surgery, were randomly divided into dezocine group ( D group) and tramadol group ( Q group) , 35 cases in each.All patients underwent general anes-thesia.D group of postoperative analgesia with dezocine +sufentanil +ondansetron;Q group of postoperative analgesia with tramadol +sufentanil +ondansetron.To observe the postoperative pain score ( VAS) , sedation score ( Ramsay) and adverse reactions.Results VAS scores of group D in 0.5 h, 3 h were lower than that of group Q, with statistical significance ( P<0.05).Ramsay scoreof group D in 3 his better than that of group Q, withstatistically significance (P<0.05).In group D, adverse reactions were also less,with statistically significancy ( P<0.05) .Conclusion The sedative effect of dezocine anal-gesiais more effective, and the side effects were significantly less, which proved it is safer for elderly patientsunder internal fix-ation of proximal humeral.