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自1996年1月至1997年6月,采用甲孕酮改善化疗患者毒副反应取得了一定效果,现将结果报告如下。 1 资料与方法 1.1 一般资料 共40例,男性26例,女性14例,中位年龄56岁(28～68岁)。全部病例均有病理或细胞学确诊。其中非小细胞肺癌15例,小细胞肺癌5例,乳腺癌10例,胃癌10例。既往手术治疗28例,化疗22例,放疗10例。 1.2 入组标准 ①入组时1个月内未接受孕激素、糖皮质激素治疗;②无胸水、腹水及水肿;③无严重心脏病及糖尿病病史;④血常规、肝肾功能正常;⑤预计生存期超过3个月以上。
From January 1996 to June 1997, the use of medroxyprogesterone to improve the toxicity of chemotherapy patients has achieved some results, and the results are reported below. 1 Materials and Methods 1.1 General Information A total of 40 cases, 26 males and 14 females, the median age of 56 years (28 to 68 years old). All cases were confirmed by pathology or cytology. Including 15 cases of non-small cell lung cancer, 5 cases of small cell lung cancer, 10 cases of breast cancer, 10 cases of gastric cancer. There were 28 cases of surgical treatment, 22 cases of chemotherapy, and 10 cases of radiotherapy. 1.2 Into the group 1 standard group 1 did not receive progesterone, glucocorticoid treatment within 1 month; 2 no pleural effusion, ascites and edema; 3 no history of severe heart disease and diabetes; 4 normal blood, liver and kidney function; The survival period is more than 3 months.