下咽癌为耳鼻咽喉头颈外科较常见的恶性肿瘤,占头颈部恶性肿瘤的3%~5%~([1]),具有早期临床表现不典型、易发生颈部淋巴结转移~([2-3]),第二原发食管癌发生率高等特点~([4]),预后很差,患者5年的生存率只有15%~45%~([5])。当前下咽癌的治疗方式包括以手术治疗为主的综合治疗及非手术保守治疗,非手术治疗包括放疗、化疗及靶向治疗等。根治性放疗或同步放化疗等非手术治疗方式对于早期下咽癌(Ⅰ期或Ⅱ期)患者可取得与手术 Hypopharyngeal carcinoma is a common malignant tumor of the otorhinolaryngology head and neck surgery, accounting for 3% ~ 5% of head and neck malignancies ~ ([1]), with early clinical manifestations of atypical, prone to cervical lymph node metastasis ~ ([2 3]), the second primary esophageal cancer with high incidence of ~ ([4]), the prognosis is poor, 5-year survival rate of patients with only 15% to 45% ~ ([5]). The current treatment of hypopharyngeal cancer, including surgical treatment based comprehensive treatment and conservative treatment of non-surgical, non-surgical treatment, including radiotherapy, chemotherapy and targeted therapy. Radical or concurrent chemoradiotherapy and other non-surgical treatment of early hypopharyngeal carcinoma (Ⅰ or Ⅱ) can be obtained with surgery