为了探讨发生妊娠期糖尿病的危险因素，对１９８８～１９９３年北医大一院确诊为妊娠期糖尿病的１１２例进行了总结分析。采用１∶１配对病例对照研究，配对条件是孕妇年龄相近（±２岁），同年同月同医院分娩。配对单因素分析表明：糖尿病家族史、慢性高血压、自然流产史、不良产史、孕次及肥胖是妊娠期糖尿病的危险因素，条件Ｌｏｇｉｓｔｉｃ回归分析引入方程的因素有糖尿病家族史（ＯＲ＝１５．０７）、肥胖（ＯＲ＝３．９９）及孕次（ＯＲ＝２．５８），表明这些因素具有独立的作用 In order to investigate the risk factors of gestational diabetes mellitus, 112 cases diagnosed with gestational diabetes mellitus in the First Affiliated Hospital of Beijing Medical University from 1988 to 1993 were analyzed. A 1: 1 paired case-control study, matching conditions are similar to the age of pregnant women (± 2 years), the same month the same month with the hospital childbirth. Paired univariate analysis showed that family history of diabetes mellitus, chronic hypertension, history of spontaneous abortion, history of poor birth, pregnancy time and obesity were risk factors of gestational diabetes mellitus. Conditioned Logistic regression analysis included the family history of diabetes (OR = 15 .07), obesity (OR = 3.99) and gestational age (OR = 2.58), indicating that these factors have independent effects