心肌肌钙蛋白 T(c Tn T)是调节心脏肌肉收缩的肌钙蛋白复合体组成之一 ,在人的心脏有 4种 c Tn T异构体 ,不同的发育阶段表达不同的 c Tn T异构体。目前发现在心力衰竭终末期 c Tn T4再度表达 ,因此 ,为进一步探讨心衰的发病机制 ,心肌肌钙蛋白 T的分子生物学基础相关研究已成为热点。 Cardiac troponin T (c Tn T) is one of the components of the troponin complex that regulates cardiac muscle contraction. There are four cTn T isoforms in the human heart that express different c Tn T isoforms at different developmental stages Structure. It has been found that cTn T4 is re-expressed in the terminal phase of heart failure. Therefore, in order to further explore the pathogenesis of heart failure, the related molecular biology of cardiac troponin T has become a hot spot.