患者男,30岁。头皮丘疹1年余。皮肤科情况:上头皮可见约十余个皮色丘疹,呈圆形或类圆形,大小约0.1cm~0.6cm不等。质地稍硬,表面略粗糙,中央见一脐形凹陷,内有淡黄色角质物质。皮损组织病理:镜下可见一扩张毛囊,表皮呈杯状凹陷,扩张毛囊内可见角质样物质,其下方可见圆体和谷粒,表皮棘层松解,局部形成假性绒毛。结合临床及病理检查诊断为多发性疣状角化不良瘤。 Male patient, 30 years old. Scalp papules more than 1 year. Dermatology: on the scalp can be seen about more than 10 skin color papules, was round or round, the size of about 0.1cm ~ 0.6cm range. Slightly hard texture, slightly rough surface, see a central umbilical depression, there are pale yellow horny material. Skin lesions: a microscopic appearance of the expansion of hair follicles, the cup was hollow epidermis, dilated hair follicles can be seen keratin-like material, which can be seen below the round body and grain, epicardial acantholysis, the local formation of false hair. Combined with clinical and pathological diagnosis of multiple verrucous keratosis.