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[目的]观察中西医结合治疗酒精性肝病的疗效及安全性。[方法]将180例患者按就诊单双号随机分为两组,中西医结合治疗组使用中药制剂保肝汤联合硫普罗宁片100mg,3次/d;西药对照组使用硫普罗宁片100mg,3次/d,治疗8周进行疗效判定。[结果]4周后治疗组总有效率为94.4%,对照组总有效率为66.6%,治疗组疗效优于对照组(P(0.05)。不良反应发生率治疗组为5.6%,低于对照组20%(P<0.05)。[结论]中西医结合治疗酒精性肝病疗效好,副作用少。
[Objective] To observe the efficacy and safety of integrated traditional Chinese and western medicine in the treatment of alcoholic liver disease. [Methods] One hundred and eighty patients were randomly divided into two groups according to the treatment single and double numbers. The traditional Chinese and western medicine combined treatment group used Chinese medicine Baogan Decoction and tiopronin 100 mg three times a day. Western medicine control group used tiopronin 100 mg , 3 times / d, the treatment of 8 weeks to determine the efficacy. [Results] After 4 weeks, the total effective rate was 94.4% in the treatment group and 66.6% in the control group, and the curative effect in the treatment group was better than that in the control group (P <0.05). The incidence of adverse reactions in the treatment group was 5.6% (P0.05). [Conclusion] Integrative treatment of alcoholic liver disease has good curative effect with few side effects.