1例62岁男性患者因外伤自行服用土三七粉,每日约15 g。半年后,患者出现腹水。停服土三七。在当地医院接受保肝治疗无效并出现重度黄疸和肝性脑病,遂转入我院。实验室检查:血小板计数13×109/L,蛋白总量37 g/L,胆红素总量128.9μmol/L,直接胆红素103.3μmol/L,丙氨酸转氨酶104 U/L,肌酐298μmol/L,尿素氮38.1 mmol/L,尿酸975μmol/L,凝血酶原时间31.7 s,凝血酶原活动度26%,C反应蛋白16 mg/L,肌酸激酶383 U/L。诊断为药物引起的肝静脉闭塞性疾病。虽经保肝、退黄、抗炎、利尿、营养等治疗,但患者进展为多器官功能衰竭,最终死亡。 A 62-year-old male patient was given soil Sanchi powder by trauma, about 15 g per day. Six months later, the patient developed ascites. Stop taking soil thirty-seven. In the local hospital to accept treatment of liver failure and severe jaundice and hepatic encephalopathy, then transferred to our hospital. Laboratory tests included platelet count 13 × 109 / L, total protein 37 g / L, total bilirubin 128.9 μmol / L, direct bilirubin 103.3 μmol / L, alanine aminotransferase 104 U / L, creatinine 298 μmol / L, urea nitrogen 38.1 mmol / L, uric acid 975 μmol / L, prothrombin time 31.7 s, prothrombin activity 26%, C-reactive protein 16 mg / L, creatine kinase 383 U / L. Diagnosis of drug-induced hepatic vein occlusive disease. Although the liver, yellow, anti-inflammatory, diuretic, nutrition and other treatment, but the progress of patients with multiple organ failure, the final death.