我们在临床实践中发现，长期应用消心痛可产生耐药性。而加用卡托普利可以防止消心痛的耐药性，现报道如下。１　对象与方法１．１　对象：按ＷＨＯ诊断标准确诊的冠心病稳定的心绞痛患者６２例，临床随机分为预防组３２例和对照组３０例。预防组男１８例，女１４例，年龄４５ We found in clinical practice, long-term use of anti-heart pain can produce resistance. The addition of captopril can prevent ecstasy of resistance, are reported below. 1 Subjects and Methods 1.1 Subjects: 62 patients with stable angina pectoris diagnosed according to WHO diagnostic criteria were randomly divided into prevention group of 32 patients and control group of 30 patients. Prevention group of 18 males and 14 females, age 45