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本文应用酶联免疫法(ELISA)检测了40例急性病毒性脑炎患儿外周血白细胞介素2(IL-2)分泌细胞及 NK 细胞(CD_(16)~+)百分率。结果表明:急性期 IL-2分泌细胞及自然杀伤细胞(NK 细胞)均明显高于对照组,随着病程的延长逐渐下降。恢复期虽与对照组有差异,但却较急性期明显下降,差异显著。急性期 IL-2与 NK 细胞的变化呈正相关。这种改变可能系病毒感染早期机体的免疫防御反应,可能是病毒性脑炎发病原因之一。
Enzyme-linked immunosorbent assay (ELISA) was used to detect the percentage of peripheral blood interleukin-2 (IL-2) secreting cells and NK cells (CD_ (16) ~ +) in 40 children with acute viral encephalitis. The results showed that IL-2-secreting cells and natural killer cells (NK cells) in acute stage were significantly higher than those in control group, and gradually decreased with the prolongation of the course. Although the recovery of the difference between the control group, but significantly decreased compared with the acute phase, the difference was significant. Acute phase of IL-2 and NK cells was positively correlated. This change may be the body’s immune defense response early virus infection may be one of the causes of viral encephalitis.