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由于癌瘤细胞的某些代谢特点,如RNA和DNA合成旺盛,出现胚胎时期的蛋白质和酶、糖酵解作用增强以及激素和某些微量元素代谢的变化等。这些质和量的变化在胃癌细胞中也均有所反映。例如可能出现胃癌相关抗原、血液以及胃液中酶和同功酶的变化、代谢产物以及慢性消耗、出血等一系列的变化。提供了胃癌生化免疫学诊断的物质基础。但由于胃癌发生部位及组织学类型的多样性,给其生化免疫学的诊断也带来了很多困难。有些方法对胃癌诊断的阳性率虽然较高(一般也只在60～80%之间),但往往缺乏特异性,它们在正常人及胃良性疾患中的假阳性也较高,通常有10～25%,所以人们认为单用任何一项诊断方法都不够理想,因此有不少研究者采用几
Due to certain metabolic features of cancer cells, such as RNA and DNA synthesis, embryonic proteins and enzymes, glycolysis, and changes in the metabolism of hormones and certain trace elements occur. These changes in quality and quantity are also reflected in gastric cancer cells. For example, there may be a series of changes such as changes in gastric cancer-associated antigen, blood, and enzymes and isozymes in gastric juice, metabolites, chronic consumption, and bleeding. Provides a material basis for the diagnosis of gastric cancer biochemical immunology. However, due to the diversity of the site and histological types of gastric cancer, the diagnosis of biochemical immunology has also brought a lot of difficulties. Some methods have a high positive rate for the diagnosis of gastric cancer (usually only between 60 and 80%), but often lack specificity, and they have higher false positives in normal people and benign gastric diseases, usually 10 to 25%, so people think that any single diagnosis method is not ideal, so many researchers use several