目的:观察麒麟丸联合芬吗通对薄型子宫内膜厚度及类型、血流和妊娠率的临床疗效。方法:前瞻性研究76例薄型子宫内膜不孕患者,随机分为对照组和研究组各38例,对照组经阴道给予芬吗通,研究组在对照组的基础上联合口服麒麟丸进行治疗。比较对照组和研究组治疗3个周期后子宫内膜厚度、类型、血流、血雌激素(E2)浓度情况和治疗半年后的自然妊娠率。结果:对照组和研究组治疗3个周期后的子宫内膜厚度、类型、血流、E2浓度情况均有明显改善(P<0.05),且研究组子宫内膜厚度和血流优于对照组,差异均有统计学意义(P<0.05);治疗半年后自然妊娠率研究组显著高于对照组(52.6%vs 28.9%),差异有统计学意义(P<0.05);研究组和对照组中妊娠患者子宫内膜厚度、类型、血流分别与本组中未妊娠患者比较,差异均有统计学意义(P<0.05)。结论:麒麟丸联合芬吗通治疗因子宫内膜薄而致的不孕,可有效改善子宫内膜厚度及血流,提高治疗半年后的自然妊娠率。 Objective: To observe the clinical effect of Kirin Pills combined with Finnant on the thickness and type of thin endometrium, blood flow and pregnancy rate. Methods: A prospective study of 76 patients with thin endometrial infertility were randomly divided into control group and study group, 38 cases in each group. The control group received fentanyl through the vagina. The study group was treated with Kirin pellet on the basis of the control group . The endometrial thickness, type, blood flow, blood estrogen (E2) concentration and the natural pregnancy rate after six months of treatment were compared between the control group and the study group. Results: The endometrial thickness, type, blood flow and E2 concentration in control group and study group were significantly improved after 3 cycles of treatment (P <0.05), and the endometrial thickness and blood flow in study group were better than those in control group (P <0.05). After 6 months of treatment, the rate of natural pregnancy in study group was significantly higher than that in control group (52.6% vs 28.9%, P <0.05), and the difference between study group and control group The thickness, type and blood flow of endometrial in patients of middle pregnancy were respectively compared with those of non-pregnant women in this group (P <0.05). Conclusion: Kirin Pills combined with fentangtong treatment of thin endometrial infertility can effectively improve the endometrial thickness and blood flow, improve the natural pregnancy rate after six months of treatment.