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目的：研究化疗药物对腺样囊性癌及腺癌的临床疗效。方法：应用５－ 氟脲嘧啶对１０ 例口腔腺样囊性癌、５ 例腺癌进行化疗，每次５００ ｍｇ，每日１ 次静推；并辅以鲨肝醇、利血生、维生素Ｂ６ 及对症治疗。结果：近期完全缓解４ 例，部分缓解９ 例，稳定２ 例；化疗后出现胃肠道反应及骨髓抑制，以纳差、恶心、呕吐、血性腹泻及白细胞总数下降为主。结论：腺样囊性癌及腺癌细胞分化程度较高，故恶性程度较低，对放射治疗敏感性不高，采用单纯化疗或化疗加手术的方法比较理想。
Objective: To study the clinical efficacy of chemotherapy drugs on adenoid cystic carcinoma and adenocarcinoma. Methods: 5-fluorouracil was used to treat 10 cases of oral adenoid cystic carcinoma and 5 cases of adenocarcinoma with chemotherapy, 500 mg each time, 1 infusion per day; supplemented with shark liver alcohol, leucogen, vitamin B6 And symptomatic treatment. Results: In the near future, 4 cases were completely relieved, 9 cases were partially relieved, and 2 cases were stable. Gastrointestinal reaction and myelosuppression occurred after chemotherapy, which mainly consisted of anorexia, nausea, vomiting, bloody diarrhea, and a decrease in the total number of white blood cells. Conclusion: Adenoid cystic carcinoma and adenocarcinoma cells are highly differentiated, so the degree of malignancy is low, and sensitivity to radiation therapy is not high. It is ideal to use chemotherapy alone or chemotherapy plus surgery.