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Objective: This prospective clinical study evaluated the dentoskeletal changes in class Ⅱ malocclusion patients treated with Twin Block functional appliance(TB).Method: Cephalometric analysis of the fourty patient samples before and after treatment divided in two groups, Twin Block treated group and untreated control group where to assess the data changes of points and angles of maxilla and mandible. Results: A class Ⅰ molar relationship was achieved in 21 subjects of the TB group, while no modification occurred in 19 subjects of control group.There were some trace changes in maxillary bones and some vertical, anterior posterior facial height changes were also observed.Moreover, a significant increase in total mandibular length and an anterior displacement of mandibular position and overjet reduction occurred in the treated group (p<0.05). Conclusion: Class Ⅱ treatment with the Twin block appliance in Chinese patients showed skeletal and dental effects, including increased in mandibular length and incisors compensation respectively.