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Although several attempts relying on classical theories on nanofluid like the continuum Hagen-Poiseuille relation have failed,we theoretically investigate the basic law of flow within nanotubes by considering the fluid inhomogeneity at the fluid-solid interfaces.The newly derived model for the calculation of nanofluidic penetration rates can explain the flow enhancement previously reported in the literature.This model can be gradually simplified along with the relieved confinement and finally reduced into the Hagen-Poiseuille relation.The model can be verified by dissipative particle dynamics(DPD)simulations.