Thrombus causes the thrombosis such as cerebral and myocardial infarctions,and accounts for an enormous rate of its death in Japan.The disease is induced by unusual dot formation and impaired thrombolytic function with age,for example.This becomes life-threatening if it occurs,and an extraordinary cost of medical expenses is needed for the treatment.Therefore,in order to keep up a good-life with health it is important to support antithrombotie and fibrinolytic actions in daily life.