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5. Silica nanoparticles induce liver fibrosis via TGF-β1/Smad3 pathway in vivo

Silica nanoparticles induce liver fibrosis via TGF-β1/Smad3 pathway in vivo

来源 :中国毒理学会纳米毒理学专业委员会第五届全国纳米生物效应与毒理学会议暨中国纳米医学会议2016(China Nanomed | 被引量 : 0次 | 上传用户：sevenzzzz

【摘 要】

：

The toxic mechanism of silica nanoparticles(SiNPs) on liver which is the main scavenger for blood borne xenobiotics still remains unclear.This study was to explore the hepatic toxicological mechanisms

【作 者】

：

Yang Yu Junchao Duan Yang Li Yanbo Li Li Jing Man Yang Ji Wang Zhiwei Sun 

【机 构】

：

School of Public Health,Capital Medical University,Beijing,100069,P.R.China;Beijing Key Laboratory o

【出 处】

：

中国毒理学会纳米毒理学专业委员会第五届全国纳米生物效应与毒理学会议暨中国纳米医学会议2016(China Nanomed

【发表日期】

：

2016年3期

【关键词】

：

Silica nanoparticles Oxidative damage Apoptosis Fibrosis Transforming growth fac 

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　　The toxic mechanism of silica nanoparticles(SiNPs) on liver which is the main scavenger for blood borne xenobiotics still remains unclear.This study was to explore the hepatic toxicological mechanisms of SiNPs.

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