Maf1 regulation of mitochondrial function mediates TOR signaling for longevity

来源 :2014 International Conference on Aging and Disease(2014年第一届衰 | 被引量 : 0次 | 上传用户:kuyedie222
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  Calorie restriction (CR) can extend lifespan of various species, ranging from single organisms such as budding yeast to human.The target ofrapamycin complex 1 (TORC1)has recently been shown to be a critical modulator of CR-induced lifespan extension.However, the underlying mechanisms remain poorly understood.
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