鼻咽癌调强放疗后放射性颞叶损伤的临床观察

来源 :第七届全国鼻咽癌学术大会 | 被引量 : 0次 | 上传用户:peng6265066
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  [目的]研究鼻咽癌调强放疗后放射性颞叶损伤的影像及临床特点.[方法]回顾性研究单治疗组2005年3月至2012年1月初治无远处转移鼻咽低分化鳞癌患者行IMRT共260例.依据08分期:Ⅰ期12例(4.6%),Ⅱ期36例(13.8%),Ⅲ期103例(39.6%),Ⅳ期109例(41.9%),局部晚期T3/T4患者共162例,放疗剂量:GTVnx 61.32~76Gy/28~35f,GTVnd 60~75Gy/28~34f,CTV1 56~60Gy/28~32f,CTV2 50~52Gy/28f.19例患者未行化疗,余患者均进行了以铂类为基础的诱导或同步化疗1~2个周期,仅16例患者行巩固化疗1~3个周期.放疗后行系列MRI随访,末次随访时间2015-1-31.
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