【摘 要】
：
We present a novel gold bellflower(GBF)platform with multiple-branched petals,prepared by a liquid-liquid-gas triphase interface system,for photoacoustic imaging(PAI)-guided photothermal therapy(PTT).
【出 处】
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中华放射学学术大会2016、中华医学会第23次全国放射学学术大会暨中华医学会第24次全国影像技术学术大会
论文部分内容阅读
We present a novel gold bellflower(GBF)platform with multiple-branched petals,prepared by a liquid-liquid-gas triphase interface system,for photoacoustic imaging(PAI)-guided photothermal therapy(PTT).Upon near-infrared(NIR)laser irradiation,the GBFs,with strong NIR absorption,showed very strong PA response and an ultrahigh photothermal conversion efficiency(η,74%)among the reported photothermal conversion agents.The excellent performance in PAI and PTT is mainly attributed to the unique features of the GBFs:(ⅰ)multiple-branched petals with an enhanced local electromagnetic field,(ⅱ)long narrow gaps between adjacent petals that induce a strong plasmonic coupling effect,and(ⅲ)a bell-shaped nanostructure that can effectively amplify the acoustic signals during the acoustic propagation.Besides the notable PTT and an excellent PAI effect,the NIRabsorbing GBFs may also find applications in NIR light-triggered drug delivery,catalysis,surface enhanced Raman scattering,stealth,antireflection,IR sensors,telecommunications,and the like.
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