Objective The Bromodomain and Extra-Terminal Domain(BET)family of proteins,including BRD2,BRD3,BRD4,and BRDT in mammalian cells,are epigenetic readers that bind to acetylated-lysine residues in histon
Objective In this study,we aimed to investigate the combined effect of Trastuzumab plus recombinant human Endostatin(rh-endostatin)on SK-BR3 breast carcinoma cells in vivo,and its underlying mechanism
Objective Indoleamin-2,3-dioxygenase-1(IDO1),has been identified as a checkpoint protein involved in generating the immunosuppressive tumor microenvironment that supports tumor growth.