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Enhancement of whitening effects and UV protection activities from Angelica gigas Nakai by ultra high pressure extraction process were investigated on several extraction process.Extraction at 60℃ treated by ultra high pressure for 15 minute and associated with ultrasofication (HPE15) was showed more than double yield,compare conventional extraction,as 12.24%(w/w) from A.gigas.Extracts of HPE15 reduced about 55.7% expression of MMP-1 on UV-irradiated CCD-986sk cells and revealed high inhibitory potency on tyrosinase as 69.4% by adding samples of 1.0 mg/ml concentration.