Osteoarthritis(OA)is degenerative joint disease,typified by a loss of quality of cartilage and bone at the interface of a joint.It affects over 18%of population when they reach their mid-fifties.This figure rises to over 52%by the time they reach their mid-70s.Individuals with OA often experience joint pain and reduced joint function unless appropriate treatment is adopted.When the loss of cartilage and bone has progressed to the stage where there is no alternative but a joint replacement in an end-stage treatment.