Background: Phospholipase C,β1(PLCB1)plays critical roles in intracellular transduction and regulating signal activation which are important to tumorigenesis.
Purpose: To evaluate the efficacy,safety,and optimal dose of EW-7197,an activin receptor-like kinase 5(ALK-5)inhibitor,in prevention of granulation tissue formation following bare metallic stent place
Purpose: To investigate the efficacy of EW-7197 in preventing granulation tissue formation caused by bare metallic stent placement and to evaluate the anti-fibrosis therapeutic potential of blocking T
Propose: To explore the potential disease process of hepatocellular carcinoma(HCC)and identify information regarding HCC-related miRNAs or marker genes for the gene therapy of HCC.