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Normal thyroid physiology during pregnancy· hCG rises after conception and peaks between 7-11 weeks.· hCG shares the same α subunit of TSH-＞stimulation of thyroid hormone production and secretion-＞ suppression of TSH Normal thyroid physiology during pregnancy· TBG (甲状腺球蛋白): starts to rise at 6-8weeks, peaks at 18-20 weeks, and stays at plateau