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Benzo(a)pyrene (BaP) is a ubiquitously distributed environmental pollutant and a known carcinogen that can induce malignant transformation of rodent and human cells.Poly(ADP-ribose) glycohydrolase (PARG) is an enzyme that catalyzes the degradation of poly-ADP-ribose (PAR) and plays an important role in DNA repair, genomic stability and carcinogenesis.