Suppression of enhancer over-activation by a RACK7-histone demethylase complex

来源 :第十一次全国基因功能与表观遗传调控学术研讨会 | 被引量 : 0次 | 上传用户:wilson168168
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Primed enhancers are marked by histone H3K4 mono-methylation (H3K4me1), and the conversion to active enhancers involves acetylation of histone H3K27 (H3K27Ac).
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In mammals, active DNA demethylation involves oxidation of 5-methylcytosine (5mC) into 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) by Tet dioxygenases
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