Objective To evaluate the prognosis of different ways of drainage for patients with malignant obstructive jaundice.Materials and Methods During the period of January 2008-March 2014,percutaneous transhepatic catheter drainage(PTCD)/percutaneous transhepatic biliary stenting(PTBS)were performed for 156 patients.According to percutaneous transhepatic cholangiography(PTC),external drainage was selected if the region of obstruction could not be passed by guide wire or a metallic stent was inserted if it could.External drainage was the first choice if infection was diagnosed before the procedure,and a metallic stent was inserted in one week after the infection was under control.Selection by new infections,the degree of bilirubin decrease,the change of ALT,the time of recurrence of obstruction,and the survival time of patients as the parameters was conducted to evaluate the methods of different interventional treatments regarding prognosis of patients with hilar obstruction caused by hilar cholangiocarcinoma.Results PTCD was conducted in 7 patients and PTBS in 9(p<0.05).Reduction of bilirubin levels and ALT levels was obvious after the procedures(p<0.05).The average survival time with PTCD was 173 days and with PTBS was 252 days(p<0.05).Conclusions With both drainage procedures for malignant obstructive jaundice improvement in liver function was obvious.PTBS was found to be better than PTCD for prolonging the patient survival time.