Ponatinib inhibits proliferation and induces apoptosis of liver cancer cells by affecting multiple s

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户:lijie041132
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  Ponatinib is a multi-target protein tyrosine kinase inhibitor,and its effects on HCC have not been previously explored.In the present study,we investigated its effects on HCC cell growth and the underlying mechanisms.Among a panel of tyrosine kinase inhibitors,ponatinib most effectively decreased the proliferation of three HCC cell lines,SK-HEP-1,SNU-423 and Bel-7402.
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