Efficient Production of Fatty Alcohols by E.coli Modified with Tandem Repeats Assisted Genome Editin

来源 :第七届中日化工学术研讨会 | 被引量 : 0次 | 上传用户：lleii

【摘要】

：

　　Genome editing can introduce predetermined sequence changes to the target genome.In this work,a new genome editing method of tandem repeat assisted genome e

【作者】

：

JianminXing[1]YilanLiu[2]QinhongWang[2]YanheMa[2]

【机构】

：

Institute of Process Engineering,Chinese Academy of Sciences,Beiertiao 1,Zhongguancun,Beijing 100190

【出处】

：

第七届中日化工学术研讨会

【发表日期】

：

2015年期

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　　Genome editing can introduce predetermined sequence changes to the target genome.In this work,a new genome editing method of tandem repeat assisted genome editing(TRAGE)was developed.This method can realize seamlessly deleting,substituting or inserting targeted genes in genome by one round of genetic manipulation with high fidelity.TRAGE was applied in the construction of recombinants for fatty alcohol production.

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Efficient Production of Fatty Alcohols by E.coli Modified with Tandem Repeats Assisted Genome Editin

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