Direct cyanation at the α-position of nitrogen-containing heterocycles such as tetrahydroisoquinolines is an attractive method for the formation of α-amino nitriles which are highly versatile because
In 1980s Haruta found that Au nanoparticles(NPs) smaller than 5 nm were highly active in low-temperature CO oxidation [1,2].Since then,great efforts have been devoted to this model reaction.