【摘 要】
：
a member of transforming growth factor β (TGF-β) family, mostly expressed in skeletal muscles and known to play a crucial role in the negative regulation
【机 构】
：
Research Center for Laboratory Animal Science of Inner Mongolia University,Hohhot 010070
论文部分内容阅读
a member of transforming growth factor β (TGF-β) family, mostly expressed in skeletal muscles and known to play a crucial role in the negative regulation of muscle growth.Follistatin (FSTN), also known as a suppressor protein of FSH, is a single chain glycoprotein.FSTN can combine with MSTN to block the function of MSTN, and promote muscle growth.MSTN knockout or knockdown and over-expression of FSTN can induce the target animals with significant increase in muscle masses.In this experiment, we constructed interference vectors of MSTN and detected the interference efficiency, and obtained two interference vectors which can disturb the expression of MSTN with high efficiency.
其他文献
为获得高表达且特异性针对牛病毒性腹泻病毒E2主要抗原表位的纳米抗体,构建抗BVDV纳米抗体基因文库,并利用噬菌体展示技术从库中筛选出特异结合BVDV-E2的纳米抗体,为防治BVDV
绵羊季节产羔导致母羊利用率低下，这是现代绵羊高效养殖的一个瓶颈.国内外研究表明绵羊产羔性状是受多基因控制的数量性状，其遗传力相对较低.随着分子生物学技术的迅速发展
Karyopherins also called Importins, including alpha-and beta-type, are important transport proteins in eukaryotic cells that carry cargoes across nuclear po
CRISPR/Cas9 has been applied in human cells and many organisms for targeting a specific genome locus.Meanwhile, to efficiently enrich genetically modified c
多不饱和脂肪酸去饱和酶基因(FAD3)编码的ω-3去饱和酶能够将ω-6多不炮和脂肪酸转化成ω-3多不饱和脂肪酸。哺乳动物自身不能合成ω-3脂肪酸，只能从食物中摄取，故通过转FA
Myostatin, also known as growth/differentiation factor-8 (GDF-8), is a member of transforming growth factorβ(TGF-β) family, mostly express in skeletal mus
Due to public concerns about transgenic organisms, it is necessary to establish valid protocols for constructing vectors with safety and expression efficien
Backgroud: MicroRNAs are a class of endogenous non-coding small RNA, which can regulate gene expression through specific degradation of mRNAs or inhibiting
免疫球蛋白是动物获得性免疫系统的重要组成部分，存在于鱼类、两栖类、爬行类、鸟类和哺乳类所有有颌动物中。目前关于人和小鼠免疫球蛋白的基因座结构和类型等研究比较清
毛发和皮肤的颜色是哺乳动物重要的特征之一，毛色的形成过程复杂，基因、环境、饲料/食物等都对毛色的形成有影响.项目组在细毛羊育种群中发现了天然毛色突变的有色细毛羊个