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目的:探讨手术未全切除的胶质瘤患者与全切除的转归差异。方法:回顾性分析2000年1月-2004年1月108例未能手术全切除的胶质瘤患者,对预后进行单因素及多因素分析并与同期全切除的223例病例进行比较。结果:低级别组中手术未全切除的胶质瘤患者1,3年生存率与全切组无明显差异,5年生存率出现明显差异,全切组明显高于未全切组。高级别组中研究组与对照组的1年生存率差别不明显,3年及5年生存出现明显差异。结论:无论高低级别手术全切与否与胶质瘤复发及患者预后的关系极为密切。
Objective: To investigate the difference between the outcome of total resection and the surgical resection of glioma. Methods: A retrospective analysis of 108 patients with gliomas who failed to undergo total surgical resection from January 2000 to January 2004 was performed. Univariate and multivariate analyzes were performed on the prognosis and compared with 223 cases of total resection in the same period. Results: The 1-year and 3-year survival rates of patients with incomplete resection of glioma in the low-grade group were not significantly different from those in the complete resection group, and the 5-year survival rate was significantly different. The total resection group was significantly higher than the group without complete resection. There was no significant difference in 1-year survival rate between the study group and the control group in the high-grade group, and significant difference in the 3-year and 5-year survival rates. Conclusion: There is a close relationship between total and complete resection of gliomas and the prognosis of patients.