Epigenetic silencing of DACH1 in triple negative breast cancer contributes to the tumorigenesis

来源 :第四届国际肿瘤表观遗传学大会 | 被引量 : 0次 | 上传用户:JK0803_zhouli
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BACKGROUND: Increasing evidence indicates that cell fate determination factor DACH1 functions as a tumor suppressor.Specifically, in estrogen receptor positive (luminal), elevated expression of DACH1 predicted longer cancer specific survival and disease free interval, as well as reduced metastasis formation.
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