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  5. The role of an inwardly rectifying K+ channel (Kir4.1) in the inner ear

The role of an inwardly rectifying K+ channel (Kir4.1) in the inner ear

来源 :The 18th Congress of the International Federation of Associa | 被引量 : 0次 | 上传用户：jianzi
【摘 要】
：
The KCNJ10 gene which encodes an inwardly rectifying K+ channel Kir4.1 subunit plays an essential role in the inner ear and hearing.Mutations or knockout of KCNJ10 abolish endocochlear potential (EP)
【作 者】
：
Jing Chen 
【机 构】
：
Department of Morphology, Medical College of China Three Gorges University, Yichang, Hubei, P.R.Chin
【出 处】
：
The 18th Congress of the International Federation of Associa
【发表日期】
：
2014年8期
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The KCNJ10 gene which encodes an inwardly rectifying K+ channel Kir4.1 subunit plays an essential role in the inner ear and hearing.Mutations or knockout of KCNJ10 abolish endocochlear potential (EP) leading to deafness.Kir4.1 is found strongly expressed on the apical membrane of intermediate cells in the stria vascularis and in the satellite cells of cochlear ganglia.
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