【摘 要】
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Although a broad range of organic unit reactions have been developed for the construction of organic compounds, most of these reactions are incompatible with each other and cannot be conducted in the
【机 构】
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College of Chemistry Central China Normal University Wuhan 430079
【出 处】
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中国化学会全国第十一届有机合成化学学术研讨会
论文部分内容阅读
Although a broad range of organic unit reactions have been developed for the construction of organic compounds, most of these reactions are incompatible with each other and cannot be conducted in the same flask as one-pot procedures.The concept of reaction networks has been developed to address this issue of incompatibility, where multiple chemical reactions can be conducted in a single pot.This novel methodology provides an efficient strategy for the synthesis of complex compounds from simple and readily available starting materials.Using this particular strategy,a series of optimum conditions were identified for the convergent integration of a series of domino reactions into one-pot processes, including a self-sorting domino reaction, a focused domino reaction, and a self-labor domino reaction.Herein, we have developed a facile method for the synthesis of 4-aryl-2-aminothiazoles derivatives from simple and readily available aromatic ketones and thiourea.
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