IL-17A, but not IL-17F, is indispensable for airway vascular remodeling induced by exaggerated Th17

来源 :2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户：JunKao

【摘要】

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【作者】

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Shan Lu Hequan Li Guohua Lu Jianying Zhou

【机构】

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Department of Respiratory and Critical Care Medicine,First Affiliated Hospital of Zhejiang Universit

【出处】

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2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议

【发表日期】

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2014年3期

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Objective Our previous study has depicted an essential role of Th17 cells in excessive mucus secretion and airway smooth muscle proliferation in a prolonged ovalbumin (OVA)-challenged C57BL/6mouse model.However, the impact of Th17 cells against vascular remodeling, another characteristic features of airway remodeling in asthma, remains elusive.In this paper, we made further study to explore this issue.

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IL-17A, but not IL-17F, is indispensable for airway vascular remodeling induced by exaggerated Th17

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