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目的:研究血浆置换术治疗重型肝炎的疗效及安全性。方法:采用HP200血液净化治疗仪,YT50P.P血浆分离器进行血浆置换治疗各期重型肝炎患者68例,并对治疗的疗效和并发症进行分析。结果:治疗后血清TBIL、ALT、AST、PTA、NH3较治疗前明显下降(P<0.01)。68例重型肝炎患者中治愈好转29例(41.8%),死亡或自动出院39例(52.2%),未发现有严重不良反应。结论:应用血浆置换治疗重型肝炎患者具有一定疗效,且早中期患者的疗效较晚期好。
Objective: To study the efficacy and safety of plasmapheresis in the treatment of severe hepatitis. Methods: Sixty-eight patients with severe hepatitis were treated with HP200 blood purification instrument and YT50P.P plasma separator. The curative effect and complication of the therapy were analyzed. Results: After treatment, the levels of serum TBIL, ALT, AST, PTA and NH3 decreased significantly (P <0.01). Of the 68 patients with severe hepatitis, 29 were cured (41.8%), 39 were dead or discharged (52.2%), and no serious adverse reactions were found. Conclusion: The application of plasmapheresis in the treatment of severe hepatitis patients has a certain effect, and early and mid-term patients with better than the late efficacy.