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The aim of this paper is to explore effects of macroeconomic variables on house prices and also, the lead-lag relationships of real estate markets to examine house price diffusion across Asian financial centres.The analysis is based on the Global Vector Auto-Regression(GVAR) model estimated using quarterly data for six Asian financial centres (Hong Kong, Tokyo, Seoul, Singapore, Taipei and Bangkok) from 1991Q1 to 2011Q2.The empirical results indicate that the global economic conditions play significant roles in shaping house price movements across Asian financial centres.In particular, a small open economy that heavily relies on international trade such as-Singapore and Tokyo-shows positive correlations between economy s openness and house prices, consistent with the Balassa-Samuelson hypothesis in international trade.However, region-specific conditions do play important roles as determinants of house prices, partly due to restrictive housing policies and demand-supply imbalances, as found in Singapore and Bangkok.