【摘 要】
：
The critic al foundation for traditional Chinese medicine (TCM) effectiveness originates from the chemical ingredients of the raw herbal materials.It is ver
【机 构】
：
Waters China, Shanghai, China 201206
【出 处】
：
2015年第一届药代动力学朝阳论坛
论文部分内容阅读
The critic al foundation for traditional Chinese medicine (TCM) effectiveness originates from the chemical ingredients of the raw herbal materials.It is very difficult to identify chemical ingredients and deduce possible herbal composition for complete unknown products, especially the available sample background information is close to none.Here, we present a novel workflow that enables researchers to quickly identify chemical ingredients and deduce possible herbal content from unknown TCM product from a single LC-MS injection.The informatics platform processing result shows that the unknown sample commercially named XinKeShu, which contains DanShen, SanQi, GeGen, ShanZha, and MuXiang.
其他文献
A contract research organization (CRO) is an organization that provides support to the pharmaceutical, biotechnology, and medical device industries in the f
Discovery and development of therapeutic protein dugs have been a major focus in the pharmaceutical industry in recent years.Understanding pharmacokinetic/p
As a well-known Chinese medicine, Eucommia ulmoides has the function of regulating blood pressure, reducing blood sugar and fats, anti-oxidant and anti-micr
Fatty acid binding protein 4 (FABP4) has been known as a mediator of infammatory response in the macrophages and adipose tissue, but its hepatic function is
Human cytochrome P450 (CYP) 3A isoforms (mainly including CYP3A4 and CYP3A5) metabolize approximately half of the marketed drugs and thus play a critical ro
The microbiota-host co-metabolites have proven to be of great importance in physiological studies and their dysregulation has been found to be closely relat
Shenxiong Glucose Injection is a compound preparation from Salvia miltiorrhiza (SM, also called Danshen) and ligustrazine hydrochloride (LZH), and it has be
Human cytochrome P450 1A (CYP1A), one of the most important phase Ⅰ important drug-metabolizing enzymes in human, plays a significant role in metabolism of
Tolcapone and entacapone, two potent catechol-O-methyltransferase COMT inhibitors, were commonly used as therapeutic drugs for treatment of Parkinson's dise
Amino acids, neurotransmitter, purines and pyrimidines are bioactive molecules playing fundamental roles in maintaining various physiological functions.Thei